Research

New Materials, Single Molecule Biophysics and Spectroscopy

We are interested in the design, implementation, and characterization of new tools for imaging and manipulation of “hard” (inorganic) and “soft” (biological) materials. One aim is to produce hybrid materials that combine the interesting electronic/optical properties of inorganic materials with the structural properties of biological materials. We are currently also developing new probes and sensing schemes to characterize the function and dynamics of individual biological molecules and complexes. The ultimate goal of these studies is to generate reliable tools that can grant insight into fundamental biological processes on a single molecule level.

People

Bjoern M. Reinhard (bmr at bu.edu)

Assistant Professor of Chemistry

postdoc, UC Berkeley, 2004-2007

PhD, Technische Universitaet Kaiserslautern (Germany), 2003

Diploma, Technische Universitaet Muenchen (Germany), 2000

BS, Universitaet Bielefeld (Germany), 1997

Linglu Yang   (lyang  at bu.edu)                                            

postdoc                                                 

PhD, Peking University (China), 2005

  

 

Lynell Skewis (skewis at bu.edu)

gradstudent 

BS, University of Washington, 2006

 

  

 

  

Hongyun Wang (whongyun at bu.edu)

gradstudent

BS, University of Science and Technology of China, 2007 

 

 

Guoxin Rong (gxrong at gmail.com)

gradstudent

BS, University of Science and Technology of China, 2007



Bo Yan (yanbo at bu.edu)

gradstudent

BS, Fudan University (China), 2007 

 

Anu Thubagere (anu.thubagere at gmail.com)

gradstudent

MS, Oklahoma State, 2007 

 

 

  Tarik Silk, BU undergraduate (Chem)

 

 

 

 

Stacey Capehart, NSF-REU

 

 

 

 

 

Karla Mercado, BU undergraduate (BME) 



 

** We have a limited number of open positions. If you are interested in joining the group, please contact Bjoern**

Alumni

Location & Contact

We are located on the 4th floor of the Chemistry Department in the Metcalf Science Center (590 Commonwealth Avenue).

Bjoern's office: SCI 452 (phone: 617-353-2498)

Grad-student office: SCI 471 (phone: 617-358-0511)

Labs: SCI 472, 478, 480

Schedule & Group Meetings: http://calendar.bmreinhard.net/ 

Materials: Posters

Publications 

  • "Photonic-Plasmonic Scattering Resonances in Deterministic Aperiodic Structures" A. Gopinath, S. Boriskina, N.-N. Feng, B. M. Reinhard, L. Dal Negro, accepted for publication in Nano Lett.  
  • "Sulfidation of Cadmium at the Nanoscale" A. Cabot, R. K. Smith, Y. Yin, H. Zheng, B. M. Reinhard, H. Liu, A. P. Alivisatos, accepted for publication in ACS Nano. 
  •  "Spermidine Modulated Ribonuclease Activity Probed by RNA Plasmon Rulers" L. R. Skewis, B. M. Reinhard, Nano Lett. 8, 214 (2008).
  • "Particle Enhanced Plasmonic NSOM" Y. Wang,  B. M. Reinhard, C. Sun, X. Zhang, Conference 6642-Proceedings of SPIE  6642, article 6642-7 (2007).
  • "Use of Plasmon Coupling to reveal the Dynamics of DNA bending and cleavage by single EcoRV restriction enzymes"   B. M. Reinhard, S. Sheikholeslami, A. Mastroianni, A. P. Alivisatos, J. Liphardt, PNAS 104, 2667 (2007).
  • "Dynamic Molecular Rulers Based on Plasmon Coupling: Performance and Resolution of 40 nm and 80 nm Gold Particle Plasmon Rulers” B. M. Reinhard, M. Siu, H. Agarwal, A. P. Alivisatos, J. T. Liphardt, Nano Lett. 5, 2246 (2005).
  • “A biocompatible force sensor with optical readout and dimensions of 6 nm3” H. Shroff, B. M. Reinhard, M. Siu, H. Agarwal, A. Spakowitz,  J. Liphardt, Nano Lett. 5, 1509 (2005).
  • "A Molecular Ruler Based on Plasmon Coupling of Single Gold and Silver Nanoparticles" C. Sonnichsen, B. M. Reinhard, J. Liphardt, A. P. Alivisatos, Nat. Biotechnology, 23, 741 (2005).
  • "Coordination versus Internal Reaction in Niobium-Acetonitrile Complexes Probed by Infrared Multiphoton Dissociation Spectroscopy” B. M. Reinhard, A. Lagutschenkov, J. Lemaire,  P. Boissel, P. Maitre and G. Niedner-Schatteburg, J. Phys. Chem. A 108, 3350 (2004).
  • "Ab initio study of [Mg,nH2O]- reactive decay products: structure and stability of magnesium oxide and magnesium hydroxide water cluster anions [MgO,(n-1)H2O]-, [HMgOH,(n-1)H2O]- and [Mg(OH)2,(n-2)H2O]- ” B. M. Reinhard, A. Lagutschenkov, G. Niedner-Schatteburg, Phys. Chem. Chem. Phys. 6, 4268 (2004).
  • "Ab initio treatment of magnesium water cluster anions [Mg,nH2O]-, n<11” B. M. Reinhard and G. Niedner-Schatteburg, Phys. Chem. Chem. Phys. 5, 1970 (2003).
  • "Ionization energies and spatial volumes of the singly occupied molecular orbital in hydrated magnesium clusters [Mg,nH2O]+ ”, B. M. Reinhard and G. Niedner-Schatteburg, J. Chem. Phys. 118, 3571 (2003).
  • "H2 Elimination from Hydrated Aluminum Clusters: Acid-Base Reactions Mediated by Intracluster Proton Transfer” B. M. Reinhard and G. Niedner-Schatteburg, J. Phys. Chem. A 106, 7988 (2002).
  • "Co-existence of hydrated electron and metal di-cation in [Mg,nH2O]+ ” B. M. Reinhard and G. Niedner-Schatteburg, Phys. Chem. Chem. Phys. 4, 1471 (2002).
  • "Wet electrons and how to dry them“ M. K. Beyer, B. S. Fox, B. M. Reinhard, and V. E. Bondybey, J. Chem. Phys. 115, 9288 (2001).
  • "Molecular recognition in the solid state: topology of experimental and theoretical charge densities for tetrasulfur tetranitride” W. Scherer, M. Spiegler, B. Pedersen, M. Tafipolsky, W. Hieringer, B. Reinhard, A. Down, G. S. McGrady, Chem. Commun. 7, 635 (2000).

Funding  

Course Material

Links

BU Chemistry

The Photonics Center

Center of Nanoscience and Nanobiotechnology